The ultimate success of training is the ability of the trainees to apply their skills in the real-life, professional field. It is imperative for a CPR certification course to build on didactic instruction with simulation learning that includes hands-on, application-based training so the trainees gain the skills and confidence required to perform this life-saving procedure in the real-life situation. Similarly, to prepare pharmaceutical sales representatives for the real-life selling scenarios, effective training materials should immerse and engage trainees. The integration of interactivity and the incorporation of active, application-based learning is especially valuable in reinforcing training materials such as virtual classroom trainings, or VCTs. Effective VCTs build on information presented in modules and capture as well as maintain the trainee’s attention by keeping them highly engaged and motivated. Furthermore, to combat the short attention span of the modern learner, trainers need to leverage technology and interactivity to successfully engage and assess the trainees.